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Biostimulatory Fillers

Procedure Time

45 minutes

Recovery Time

Up to 1 week

Number of treatments recommended

Once every 6 weeks for up to 3 sessions and then once every 12-24 months

Anesthesia

Topical numbing cream

Biostimulators are compounds that are injected into the deep layer of the skin called the dermis. Unlike hyaluronic acid dermal fillers, which simply inject volume and plump the skin, biostimulators work by stimulating new tissue growth, targeting deeper signs of aging like declining bone mass, skin sagging, and less elasticity. Biostimulatory Fillers are injected close to the bone, stimulating tissue regeneration. Their primary purpose is to stimulate the growth of your own collagen for longer-lasting fullness. Due to the increase in collagen production, biostimulatory fillers can provide a long-lasting result (18-24 months), without the need to repeat the treatment as frequently as with HA (hyaluronic acid) fillers. 

Hyperdilute Radiesse as a Biostimulatory Filler

Radiesse acts as a biostimulatory filler. When Radiesse, an injectable dermal filler consisting of calcium hydroxyapatite, is blended with saline, and injected into areas of volume loss, it can stimulate collagen production. It can be used on the arms, legs, hands, neck, chest, abdomen, and buttocks. The benefit of diluting Radiesse is to make it easily spreadable for optimal production of collagen and elastin, resulting in tighter, thicker skin, reduced wrinkles, and improved texture and tone.

Why Patients Choose Biostimulatory Fillers:

They want to address deeper signs of aging, including skin laxity, volume loss, and thinning skin. Also, because biostimulatory fillers can be used beyond the face to improve the appearance of the neck, chest, hands, arms, abdomen, and other areas where collagen loss contributes to crepey or thinning skin.

Pairs Well With:

Frequently Asked Questions

What are Biostimulatory Fillers?

Biostimulatory Fillers are injectable treatments that stimulate your body’s natural collagen production. Rather than simply filling an area, they encourage your skin to rebuild its own collagen over time, creating gradual, natural-looking improvement in firmness, support, and skin quality.

How are Biostimulatory Fillers different from Hyaluronic Acid Fillers?

Hyaluronic Acid Fillers provide immediate volume and contour by replacing lost volume with a gel-like substance. Biostimulatory Fillers work differently by stimulating your body’s own collagen production, so results develop gradually and often last longer. Many patients benefit from a combination of both treatments depending on their goals.

What areas can be treated?

Biostimulatory Fillers can be used to improve areas including:

  • Face
  • Temples
  • Jawline
  • Neck
  • Chest
  • Hands
  • Arms
  • Abdomen
  • Buttocks

Michelle will recommend the best treatment approach based on your anatomy and aesthetic goals.

When will I see results?

You may notice some initial fullness immediately after treatment, but the true results develop gradually as your body produces new collagen. Most patients begin seeing meaningful improvement over several weeks, with continued enhancement over the following months.

How long do Biostimulatory Fillers last?

Results are long-lasting because they rely on your body’s own collagen production. Depending on the product used and the treatment area, results commonly last 12 to 24 months, although individual results vary.

How many treatments will I need?

Many patients benefit from a series of up to three treatment sessions, typically spaced about six weeks apart, followed by maintenance treatments as recommended by Michelle.

Are Biostimulatory Fillers reversible?

Unlike Hyaluronic Acid Fillers, Biostimulatory Fillers are not dissolvable. For this reason, treatment should be performed by an experienced injector who understands facial anatomy and develops a personalized treatment plan. Michelle will discuss whether this treatment is appropriate for your goals during your consultation.

Am I a good candidate for Biostimulatory Fillers?

Biostimulatory Fillers are an excellent option for patients experiencing collagen loss, skin laxity, or widespread volume loss who prefer gradual, natural-looking rejuvenation. During your consultation, Michelle will determine whether a Biostimulatory Filler, a Hyaluronic Acid Filler, or a combination of both will provide the best outcome for your aesthetic goals.

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