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Restylane® ReFyne

Procedure Time

45 minutes

Recovery Time

Up to 1 week

Number of treatments recommended

Once every 6-12 months


Topical numbing cream

Before & After Pictures

Restylane® ReFyne is a hyaluronic acid dermal filler formulated with XpresHAn Technology™ and is used to soften moderate to severe facial wrinkles and folds, including nasolabial folds (smiles lines) and marionette lines (lines from the corner of your mouth down towards your chin).  This special technology allows the dermal filler to move within the face with your own natural expression.  A treatment with Restylane® ReFyne gives you results that help maintain natural movement when you’re smiling, frowning, and even puckering up.  We love this product for rejuvenating the lower face and for the lips.

Frequently Asked Questions

How long do Restylane® ReFyne treatments last?

In a clinical study of subjects treated for laugh lines with Restylane® Refyne, investigators reported improvement in the appearance of wrinkles for up to 12 months in the majority of patients.

What are the potential side effects of Restylane® ReFyne?

After your treatment, you may experience side effects, such as swelling, redness, pain, bruising, headache, itching at injection site, and tenderness. These are typically mild in severity and normally last less than 7 days.

What areas can be treated?

Restylane® Refyne is for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds, in patients over the age of 21. It can also be used to volumize the lips and the undereye area.

Before & After Pictures

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